Description
Buy PB-22 POWDER online. (QUPIC or 1-pentyl-1H-indole-3-carboxylic acid 8-quinolinyl ester) is a designer drug offer by online vendors as a cannabimimetic agent. Also, its being sold in synthetic cannabis products in Japan in 2013. However, The structure of PB-22 POWDER appears to use an understanding of structure-activity relationships. Within the indole class of cannabimimetics. Although its design origins are unclear.
However, QUPIC represents a structurally unique synthetic cannabinoid chemotype, since it contains an ester linker at the indole 3-position. Rather than the precedented ketone of JWH-018 and its analogs. The amide of APICA and its analogs. Moreover, It has an EC50 of 5.1 nM for human CB1 receptors, and 37 nM for human CB2 receptors.
More so, PB-22 produces bradycardia and hypothermia in rats at doses of 0.33 mg/kg, suggesting potent cannabinoid-like activity. More so, The magnitude and duration of hypothermia induce in rats by PB-22 POWDER is notably greater than JWH-018, AM-2201, UR-144, XLR-11. Therefore, APICA, or STS-135, with a reduction of body temperature still observable six hours after dosing. Also, One clinical toxicology study found PB-22 POWDER to be the cause of seizures in a human and his dog. Therefore, Buy PB-22 POWDER online
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